Prion protein NMR structure and familial human spongiform encephalopathies
نویسندگان
چکیده
منابع مشابه
Astrocytes in transmissible spongiform encephalopathies (prion diseases).
Astrocytosis is one of the hallmarks of neuropathology of transmissible spongiform encephalopathies (TSEs) or prion diseases. In this review, we summarize data on astrocytic reaction, including naturally occurring or experimentally induced TSEs. A particular form of astrocytic reaction is known as gliocytosis and it is typical for experimental scrapie in mouse or in hamsters. Also, astrocytes p...
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Transmissible spongiform encephalopathies (TSEs) are transmissible neurodegenerative diseases characterized by the accumulation of an abnormally folded prion protein, termed PrPSc, and the development of pathological features of astrogliosis, vacuolation, neuronal cell loss, and in some cases amyloid plaques. Although considerable structural characterization of prion protein has been reported, ...
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The Transmissible Spongiform Encephalopathies (TSEs) are a group of rare neurodegenerative diseases, which can be transmitted between members of the same species and possibly across different species. The link between the emergence of Bovine Spongiform Encephalopathy (BSE) and the new variant form of Creutzfedlt Jakob Disease (vCJD) has been the cause of much public concern. vCJD is the most wi...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1998
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.95.20.11667